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-Structure paper
Title | Crystal structure of human farnesyl pyrophosphate synthase (t201a mutant) complexed with mg and zoledronate |
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Journal, issue, pages | To be Published |
Publish date | Apr 26, 2013 (structure data deposition date) |
Authors | Tsoumpra, M.K. / Muniz, J.R.C. / Barnett, B.L. / Pilka, E. / Kwaasi, A. / Kavanagh, K.L. / Evdokimov, A.G. / Walter, R.L. / Ebetino, F.H. / Oppermann, U. ...Tsoumpra, M.K. / Muniz, J.R.C. / Barnett, B.L. / Pilka, E. / Kwaasi, A. / Kavanagh, K.L. / Evdokimov, A.G. / Walter, R.L. / Ebetino, F.H. / Oppermann, U. / Russell, R.G.G. / Dunford, J.E. |
External links | Search PubMed |
Methods | X-ray diffraction |
Resolution | 1.98 Å |
Structure data | PDB-4kfa: |
Chemicals | ChemComp-MG: ChemComp-ZOL: ChemComp-EDO: ChemComp-HOH: |
Source |
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Keywords | TRANSFERASE/TRANSFERASE INHIBITOR / Isoprene biosynthesis / Lipid synthesis / steroid biosynthesis / Transferase / isopentyl pyrophosphate and dimethylallyl pyrophosphate / Isoprenoid Pathway / Cholesterol Synthesis / Bisphosphonates / TRANSFERASE-TRANSFERASE INHIBITOR complex |