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-Structure paper
Title | Structure and mechanism of the farnesyl diphosphate synthase from Trypanosoma cruzi: Implications for drug design. |
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Journal, issue, pages | Proteins, Vol. 62, Page 80-88, Year 2005 |
Publish date | Jan 9, 2005 (structure data deposition date) |
Authors | Gabelli, S.B. / McLellan, J.S. / Montalvetti, A. / Oldfield, E. / Docampo, R. / Amzel, L.M. |
External links | Proteins / PubMed:16288456 |
Methods | X-ray diffraction |
Resolution | 1.95 - 2.5 Å |
Structure data | PDB-1yhk: PDB-1yhl: PDB-1yhm: |
Chemicals | ChemComp-SO4: ChemComp-HOH: ChemComp-MG: ChemComp-DMA: ChemComp-RIS: ChemComp-AHD: ChemComp-IPE: |
Source |
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Keywords | TRANSFERASE / farnesyl pyrophosphate synthase / farnesyl disphosphate synthase / mevalonate pathway / bisphosphonates / FPPS / farnesyl diphosphate synthase / bisphosphonate / dimethyl allyl pyrophosphate sulfate / alendronate / isopentenyl diphosphate / mevalonate patway / geranyl transferase / dimethylallyl transferase |