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Showing all 36 items for (author: gangwar & sp)

EMDB-44124:
Structure of concanavalin A (ConA) dimer from the open-state structure of kainate receptor GluK2 in complex with agonist glutamate and positive allosteric modulator BPAM344 bound to one ConA dimer. Type II interface between GluK2 ligand-binding domain and ConA
Method: single particle / : Nadezhdin KD, Gangwar SP, Sobolevsky AI

EMDB-44125:
Structure of concanavalin A (ConA) dimer from the open-state structure of kainate receptor GluK2 in complex with agonist glutamate and positive allosteric modulator BPAM344 bound to two ConA dimers. Type I interface between GluK2 ligand-binding domain and ConA
Method: single particle / : Nadezhdin KD, Gangwar SP, Sobolevsky AI

EMDB-44128:
Ligand-binding and transmembrane domains of kainate receptor GluK2 in the open state, a complex with agonist glutamate and positive allosteric modulator BPAM344
Method: single particle / : Nadezhdin KD, Gangwar SP, Sobolevsky AI

EMDB-44129:
Open state of kainate receptor GluK2 in complex with agonist glutamate and positive allosteric modulator BPAM344 bound to two concanavalin A dimers. Composite map.
Method: single particle / : Nadezhdin KD, Gangwar SP, Sobolevsky AI

EMDB-44130:
Open state of kainate receptor GluK2 in complex with agonist glutamate and positive allosteric modulator BPAM344 bound to one concanavalin A dimer. Composite map.
Method: single particle / : Nadezhdin KD, Gangwar SP, Sobolevsky AI

EMDB-44131:
Kainate receptor GluK2 in complex with agonist glutamate with pseudo 4-fold symmetrical ligand-binding domain layer
Method: single particle / : Nadezhdin KD, Gangwar SP, Sobolevsky AI

EMDB-44132:
Kainate receptor GluK2 in complex with agonist glutamate with asymmetric ligand-binding domain layer
Method: single particle / : Nadezhdin KD, Gangwar SP, Sobolevsky AI

EMDB-16052:
Cryo-EM structure of stalled rabbit 80S ribosomes in complex with human CCR4-NOT and CNOT4
Method: single particle / : Absmeier E, Chandrasekaran V, O'Reilly FJ, Stowell JAW, Rappsilber J, Passmore LA

EMDB-40741:
Structure of AMPA receptor GluA2 complex with auxiliary subunits TARP gamma-5 and cornichon-2 bound to competitive antagonist ZK and channel blocker spermidine (closed state)
Method: single particle / : Gangwar SP, Yen LY, Yelshanskaya MV, Sobolevsky AI

EMDB-40742:
Structure of LBD-TMD of AMPA receptor GluA2 in complex with auxiliary subunits TARP gamma-5 and cornichon-2 bound to competitive antagonist ZK and channel blocker spermidine (closed state)
Method: single particle / : Gangwar SP, Yen LY, Yelshanskaya MV, Sobolevsky AI

EMDB-40743:
Structure of LBD-TMD of AMPA receptor GluA2 in complex with auxiliary subunits TARP gamma-5 and cornichon-2 (apo state)
Method: single particle / : Yen LY, Gangwar SP, Yelshanskaya MV, Sobolevsky AI

EMDB-40744:
Structure of LBD-TMD of AMPA receptor GluA2 in complex with auxiliary subunit TARP gamma-5 (apo state)
Method: single particle / : Yen LY, Gangwar SP, Yelshanskaya MV, Sobolevsky AI

EMDB-40745:
Structure of AMPA receptor GluA2 complex with auxiliary subunits TARP gamma-5 and cornichon-2 bound to competitive antagonist ZK, channel blocker spermidine and antiepileptic drug perampanel (closed state)
Method: single particle / : Gangwar SP, Yen LY, Yelshanskaya MV, Sobolevsky AI

EMDB-40746:
Structure of AMPA receptor GluA2 complex with auxiliary subunits TARP gamma-5 and cornichon-2 bound to competitive antagonist ZK, channel blocker spermidine and antiepileptic drug perampanel (closed state)
Method: single particle / : Gangwar SP, Yen LY, Yelshanskaya MV, Sobolevsky AI

EMDB-40747:
Structure of AMPA receptor GluA2 complex with auxiliary subunit TARP gamma-5 bound to competitive antagonist ZK and antiepileptic drug perampanel (closed state)
Method: single particle / : Gangwar SP, Yen LY, Yelshanskaya MV, Sobolevsky AI

EMDB-40748:
Structure of LBD-TMD of AMPA receptor GluA2 in complex with auxiliary subunit TARP gamma-5 bound to competitive antagonist ZK and antiepileptic drug perampanel (closed state)
Method: single particle / : Gangwar SP, Yen LY, Yelshanskaya MV, Sobolevsky AI

EMDB-40749:
Structure of AMPA receptor GluA2 complex with auxiliary subunits TARP gamma-5 and cornichon-2 bound to glutamate and channel blocker spermidine (desensitized state)
Method: single particle / : Gangwar SP, Yen LY, Yelshanskaya MV, Sobolevsky AI

EMDB-40750:
Structure of LBD-TMD of AMPA receptor GluA2 in complex with auxiliary subunits TARP gamma-5 and cornichon-2 bound to glutamate and channel blocker spermidine (desensitized state)
Method: single particle / : Gangwar SP, Yen LY, Yelshanskaya MV, Sobolevsky AI

EMDB-29515:
Structure of kainate receptor GluK2 in complex with the positive allosteric modulator BPAM344
Method: single particle / : Gangwar SP, Yen LY, Yelshanskaya MV, Sobolevsky AI

EMDB-29516:
Structure of the amino-terminal domain of kainate receptor GluK2 in complex with the positive allosteric modulator BPAM344
Method: single particle / : Gangwar SP, Yen LY, Yelshanskaya MV, Sobolevsky AI

EMDB-29517:
Structure of the ligand-binding and transmembrane domains of kainate receptor GluK2 in complex with the positive allosteric modulator BPAM344
Method: single particle / : Gangwar SP, Yen LY, Yelshanskaya MV, Sobolevsky AI

EMDB-29518:
Structure of the amino terminal domain of kainate receptor GluK2 in complex with the positive allosteric modulator BPAM344 and competitive antagonist DNQX
Method: single particle / : Yen LY, Gangwar SP, Yelshanskaya MV, Sobolevsky AI

EMDB-29519:
Structure of the ligand-binding and transmembrane domains of kainate receptor GluK2 in complex with the positive allosteric modulator BPAM344 and competitive antagonist DNQX
Method: single particle / : Yen LY, Gangwar SP, Yelshanskaya MV, Sobolevsky AI

EMDB-29520:
Structure of the amino-terminal domain of kainate receptor GluK2 in complex with the positive allosteric modulator BPAM344 and noncompetitive inhibitor perampanel
Method: single particle / : Gangwar SP, Yen LY, Yelshanskaya MV, Sobolevsky AI

EMDB-29521:
Structure of the ligand-binding and transmembrane domains of kainate receptor GluK2 in complex with the positive allosteric modulator BPAM344 and noncompetitive inhibitor perampanel
Method: single particle / : Gangwar SP, Yen LY, Yelshanskaya MV, Sobolevsky AI

EMDB-24748:
Structure of the complex of LBD-TMD part of AMPA receptor GluA2 with auxiliary subunit TARP gamma-5 bound to agonist glutamate
Method: single particle / : Klykov OV, Gangwar SP, Yelshanskaya MV, Sobolevsky AI

EMDB-24749:
Structure of the complex of LBD-TMD part of AMPA receptor GluA2 with auxiliary subunit GSG1L bound to agonist quisqualate
Method: single particle / : Gangwar SP, Klykov OV, Yelshanskaya MV, Sobolevsky AI

EMDB-24750:
Structure of the complex of AMPA receptor GluA2 with auxiliary subunit TARP gamma-5 bound to competitive antagonist ZK 200775
Method: single particle / : Gangwar SP, Klykov OV, Yelshanskaya MV, Sobolevsky AI

EMDB-24751:
Structure of the complex of LBD-TMD part of AMPA receptor GluA2 with auxiliary subunit TARP gamma-5 bound to competitive antagonist ZK 200775
Method: single particle / : Gangwar SP, Klykov OV, Yelshanskaya MV, Sobolevsky AI

EMDB-24752:
Structure of the complex of AMPA receptor GluA2 with auxiliary subunit TARP gamma-5 bound to agonist glutamate
Method: single particle / : Klykov OV, Gangwar SP, Yelshanskaya MV, Sobolevsky AI

EMDB-24753:
Structure of the complex of AMPA receptor GluA2 with auxiliary subunit TARP gamma-5 bound to agonist Quisqualate
Method: single particle / : Klykov OV, Gangwar SP, Yelshanskaya MV, Sobolevsky AI

EMDB-24754:
Structure of the complex of LBD-TMD part of AMPA receptor GluA2 with auxiliary subunit TARP gamma-5 bound to agonist quisqualate
Method: single particle / : Klykov OV, Gangwar SP, Yelshanskaya MV, Sobolevsky AI

EMDB-24755:
Structure of the complex of AMPA receptor GluA2 with auxiliary subunit GSG1L in the apo state
Method: single particle / : Gangwar SP, Klykov OV, Yelshanskaya MV, Sobolevsky AI

EMDB-24756:
Structure of the complex of AMPA receptor GluA2 with auxiliary subunit GSG1L bound to agonist quisqualate
Method: single particle / : Gangwar SP, Klykov OV, Yelshanskaya MV, Sobolevsky AI

EMDB-23606:
Structure of the glutamate receptor-like channel AtGLR3.4
Method: single particle / : Gangwar SP, Green MN, Sobolevsky AI

EMDB-23607:
Structure of the glutamate receptor-like channel AtGLR3.4
Method: single particle / : Gangwar SP, Green MN, Sobolevsky AI

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Oct 5, 2021. Nobel Prize for mechanically activated and temperature-gated ion channels

Nobel Prize for mechanically activated and temperature-gated ion channels

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